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6 Popular American Road Trip Routes

4 minute read

By Alannah Koene

Few travel experiences capture the spirit of adventure quite like a great American road trip. From breathtaking coastlines to rugged mountain passes, the open road offers endless opportunities to explore the country’s diverse landscapes and cultures. Whether you’re chasing ocean views, desert sunsets, or historic towns, each route tells its own story. With the right plan and a sense of wanderlust, a road trip can turn the journey itself into an unforgettable part of the adventure.

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1. Rangeley Lakes National Scenic Byway

Immerse yourself into wooded forests, mountain streams, farm fields, and more along the Rangeley Lakes National Scenic Byway. This byway passes through a region of over 40,000 acres of conserved lands, making it a great place to admire nature’s beauty all year round.

Trip-goers can start at Smalls Falls on Route 4 before dropping into the village of Rangeley. This will bring you near 112 interconnected lakes and ponds spanning throughout the region. Some noteworthy places worth visiting include the Appalachian Trail, Height of Land, and Mooselookmeguntic Lake.

2. Route 66

Perhaps the most famous American road trip is Route 66. It’s a 2,400 mile trek that can take you from Chicago to Santa Monica. Since the route takes you across the country, you have plenty of cities and attractions to consider visiting along the way.

You could dedicate three weeks to travel the entire route or choose a particular stretch if you’re interested in a shorter trip. Here are a few highlights to consider:

3. Overseas Highway

Looking for a sun-filled getaway? There’s no better place than the Sunshine State. Specifically, the Overseas Highway in Florida. This 113 mile long highway connects mainland Florida to Key West. You can enjoy picturesque water views before venturing onto the Florida Keys, an area full of water sports, fishing, and lounging,

If you’re looking for a shorter day-trip, consider traveling from Miami to Florida Keys. This four hour trip will start off in a bustling city to a relaxing string of islands with an abundance of sea views.

4. Vermont Byways

Take in the views of mountains and valleys on your road trip throughout Vermont. This particular road trip consists of 10 byways that are anywhere from 14 to 400 miles long. Cruise these roads for as long as you like, whether it be for a day trip or weeklong affair

There’s plenty to see and do along the byways. This includes museums, waterfalls, hiking paths, antique shops, and lots more You can easily find various itineraries designed for foodies, outdoor recreation, historians, or other preferred activities.

5. The Outer Banks

The Outer Banks is a slim piece of land located on the northern edge of North Carolina and just south of Virginia Beach and Norfolk. This string of peninsulas and barrier islands gives you exquisite views of the Atlantic Ocean and access to plenty of sandy beaches.

There’s a full 128 mile road trip you can take to explore the Outer Banks. You can start on the National Scenic Byway and travel all the way to Ocracoke Village. Along the way, Reader’s Digest says you can enjoy sights that include wild horses and the Wright Brothers National Memorial.

6. Great River Road

There’s a lot to like about the 3,000 mile course that goes from northern Minnesota to the Gulf of Mexico. It follows the Mississippi River and takes you through 10 different states, giving you an opportunity to see much of the U.S. from one roadway.

Here are the states you can travel through on a Great River Road trip:

The entire trip will take about 36 hours of straight driving, but a good timeline to aim for is 10 days. There are tons of river-related activities to do along the way and plenty of food options as you travel from state to state.

Discover More Road Trips 

Each of these road trip routes offers its own slice of America’s beauty, history, and charm—inviting travelers to slow down and truly connect with the journey. Whether you’re winding through Vermont’s forested byways, cruising the Overseas Highway over turquoise waters, or tracing the legendary Route 66, every mile holds something new to discover. No matter which path you choose, the open road remains a timeless invitation to explore, reflect, and create memories that last long after the engine stops.

Alannah Koene

Contributor

Alannah Koene is a content writer based in Victoria, British Columbia. Although she writes for a range of topics, her professional writing often focuses on business, health, and lifestyle. Spending much of her time exploring the outdoors through sport, Alannah aims to share her perspectives through writing and content.